Acute Effects of a Single, Oral dose of d9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) Administration in Healthy Volunteers

Animal and humans studies suggest that the two main constituents of cannabis sativa, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) have quite different acute effects. However, to date the two compounds have largely been studied separately.To evaluate and compare the acute pharmacological effects of both THC and CBD in the same human volunteers.A randomised, double-blind, cross-over, placebo controlled trial was conducted in 16 healthy...