RNA Interference (RNAi)-Based Therapeutics: Delivering on the Promise?

Volume: 56, Issue: 1, Pages: 103 - 122
Published: Jan 6, 2016
Abstract
A resurgence in clinical trials using RNA interference (RNAi) occurred in 2012. Although there were initial difficulties in achieving efficacious results with RNAi without toxic side effects, advances in delivery and improved chemistry made this resurgence possible. More than 20 RNAi-based therapeutics are currently in clinical trials, and several of these are Phase III trials. Continued positive results from these trials have helped bolster...
Paper Details
Title
RNA Interference (RNAi)-Based Therapeutics: Delivering on the Promise?
Published Date
Jan 6, 2016
Volume
56
Issue
1
Pages
103 - 122
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