Endothelial Dysfunction in Cardiovascular Diseases: The Role of Oxidant Stress
Abstract
Accumulating evidence suggests that oxidant stress alters many functions of the endothelium, including modulation of vasomotor tone. Inactivation of nitric oxide (NO(.)) by superoxide and other reactive oxygen species (ROS) seems to occur in conditions such as hypertension, hypercholesterolemia, diabetes, and cigarette smoking. Loss of NO(.) associated with these traditional risk factors may in part explain why they predispose to...
Paper Details
Title
Endothelial Dysfunction in Cardiovascular Diseases: The Role of Oxidant Stress
Published Date
Nov 10, 2000
Journal
Volume
87
Issue
10
Pages
840 - 844
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