Human Pancreatic β-Cell G1/S Molecule Cell Cycle Atlas
Abstract
Expansion of pancreatic β-cells is a key goal of diabetes research, yet induction of adult human β-cell replication has proven frustratingly difficult. In part, this reflects a lack of understanding of cell cycle control in the human β-cell. Here, we provide a comprehensive immunocytochemical “atlas” of G1/S control molecules in the human β-cell. This atlas reveals that the majority of these molecules, previously known to be present in islets,...
Paper Details
Title
Human Pancreatic β-Cell G1/S Molecule Cell Cycle Atlas
Published Date
Jun 14, 2013
Journal
Volume
62
Issue
7
Pages
2450 - 2459
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