GAB2 polymorphism rs2373115 confers susceptibility to sporadic Alzheimer's disease

It has been reported that a single nucleotide polymorphism (SNP), rs2373115, in the GRB-associated binding protein 2 (GAB2) gene was associated with late-onset AD in Caucasians. Subsequently, other researchers have attempted to validate this finding in different ethnic populations. However, these findings have produced both negative and positive results. To derive a more precise estimation for whether GAB2 polymorphism rs2373115 is associated...