Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants

Nature64.80
Volume: 493, Issue: 7431, Pages: 216 - 220
Published: Jan 10, 2013
Abstract
Establishing the age of each mutation segregating in contemporary human populations is important to fully understand our evolutionary history and will help to facilitate the development of new approaches for disease-gene discovery. Large-scale surveys of human genetic variation have reported signatures of recent explosive population growth, notable for an excess of rare genetic variants, suggesting that many mutations arose recently. To more...
Paper Details
Title
Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants
Published Date
Jan 10, 2013
Journal
Volume
493
Issue
7431
Pages
216 - 220
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