A genome-wide survey of CD4+ lymphocyte regulatory genetic variants identifies novel asthma genes

Volume: 134, Issue: 5, Pages: 1153 - 1162
Published: Nov 1, 2014
Abstract
BackgroundGenome-wide association studies have yet to identify the majority of genetic variants involved in asthma. We hypothesized that expression quantitative trait locus (eQTL) mapping can identify novel asthma genes by enabling prioritization of putative functional variants for association testing.ObjectiveWe evaluated 6706 cis-acting expression-associated variants (eSNPs) identified through a genome-wide eQTL survey of CD4+ lymphocytes for...
Paper Details
Title
A genome-wide survey of CD4+ lymphocyte regulatory genetic variants identifies novel asthma genes
Published Date
Nov 1, 2014
Volume
134
Issue
5
Pages
1153 - 1162
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