The N‐myc downstream regulated gene (NDRG) family: diverse functions, multiple applications
Abstract
The N-myc downstream regulated gene (NDRG) family of proteins consists of 4 members, NDRG1-4, which are well conserved through evolution. The first member to be discovered and responsible for the family name was NDRG1, because its expression is repressed by the proto-oncogenes MYCN and MYC. All family members are characterized by an α/β hydrolase-fold motif; however, the precise molecular and cellular function of these family members has not...
Paper Details
Title
The N‐myc downstream regulated gene (NDRG) family: diverse functions, multiple applications
Published Date
Jul 28, 2010
Journal
Volume
24
Issue
11
Pages
4153 - 4166
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