Genome-Wide Association Study Implicates PARD3B-Based AIDS Restriction
Abstract
Background. Host genetic variation influences human immunodeficiency virus (HIV) infection and progression to AIDS. Here we used clinically well-characterized subjects from 5 pretreatment HIV/AIDS cohorts for a genome-wide association study to identify gene associations with rate of AIDS progression.
Methods. European American HIV seroconverters (n = 755) were interrogated for single-nucleotide polymorphisms (SNPs) (n = 700,022) associated...
Paper Details
Title
Genome-Wide Association Study Implicates PARD3B-Based AIDS Restriction
Published Date
May 15, 2011
Volume
203
Issue
10
Pages
1491 - 1502
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