Mechanisms of obesity-associated insulin resistance: many choices on the menu

Volume: 21, Issue: 12, Pages: 1443 - 1455
Published: Jun 15, 2007
Abstract
Obesity-associated insulin resistance is a major risk factor for type 2 diabetes and cardiovascular disease. In the past decade, a large number of endocrine, inflammatory, neural, and cell-intrinsic pathways have been shown to be dysregulated in obesity. Although it is possible that one of these factors plays a dominant role, many of these factors are interdependent, and it is likely that their dynamic interplay underlies the pathophysiology of...
Paper Details
Title
Mechanisms of obesity-associated insulin resistance: many choices on the menu
Published Date
Jun 15, 2007
Volume
21
Issue
12
Pages
1443 - 1455
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