Local and sex-specific biases in crossover vs. noncrossover outcomes at meiotic recombination hot spots in mice

Volume: 29, Issue: 16, Pages: 1721 - 1733
Published: Aug 6, 2015
Abstract
Meiotic recombination initiated by programmed double-strand breaks (DSBs) yields two types of interhomolog recombination products, crossovers and noncrossovers, but what determines whether a DSB will yield a crossover or noncrossover is not understood. In this study, we analyzed the influence of sex and chromosomal location on mammalian recombination outcomes by constructing fine-scale recombination maps in both males and females at two mouse...
Paper Details
Title
Local and sex-specific biases in crossover vs. noncrossover outcomes at meiotic recombination hot spots in mice
Published Date
Aug 6, 2015
Volume
29
Issue
16
Pages
1721 - 1733
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