Low-Density Lipoprotein Cholesterol and the Risk of Cancer: A Mendelian Randomization Study
Volume: 103, Issue: 6, Pages: 508 - 519
Published: Feb 1, 2011
Abstract
Low plasma levels of low-density lipoprotein (LDL) cholesterol are associated with an increased risk of cancer, but whether this association is causal is unclear.We studied 10 613 participants in the Copenhagen City Heart Study (CCHS) and 59 566 participants in the Copenhagen General Population Study, 6816 of whom had developed cancer by May 2009. Individuals were genotyped for PCSK9 R46L (rs11591147), ABCG8 D19H (rs11887534), and APOE R112C...
Paper Details
Title
Low-Density Lipoprotein Cholesterol and the Risk of Cancer: A Mendelian Randomization Study
Published Date
Feb 1, 2011
Volume
103
Issue
6
Pages
508 - 519
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