GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Abstract
A genome-wide association study (GWAS) of educational attainment was conducted in a discovery sample of 101,069 individuals and a replication sample of 25,490. Three independent single-nucleotide polymorphisms (SNPs) are genome-wide significant (rs9320913, rs11584700, rs4851266), and all three replicate. Estimated effects sizes are small (coefficient of determination R(2) ≈ 0.02%), approximately 1 month of schooling per allele. A linear...
Paper Details
Title
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Published Date
Jun 21, 2013
Journal
Volume
340
Issue
6139
Pages
1467 - 1471
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