The relationship between aging and carcinogenesis: a critical appraisal

Volume: 45, Issue: 3, Pages: 277 - 304
Published: Mar 1, 2003
Abstract
The incidence of cancer increases with age in humans and in laboratory animals alike. There are different patterns of age-related distribution of tumors in different organs and tissues. Aging may increase or decrease the susceptibility of various tissues to initiation of carcinogenesis and usually facilitates promotion and progression of carcinogenesis. Aging may predispose to cancer by several mechanisms: (1) tissue accumulation of cells in...
Paper Details
Title
The relationship between aging and carcinogenesis: a critical appraisal
Published Date
Mar 1, 2003
Volume
45
Issue
3
Pages
277 - 304
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