Investigation of the dynamic stereochemistry of dimesityl‐2,4,6‐trimethoxyphenylmethane by complete lineshape analysis and 2D EXSY NMR spectroscopy

The static and dynamic stereochemistry of dimesityl-2,4,6-trimethoxyphenylmethane in solution was investigated by lineshape analysis of 1D NMR spectra and cross-peak amplitude processing in 2D EXSY spectra, recorded at variable temperatures. Previous studies on this propeller-shaped chiral compound show that the stereomer threshold interconversion is associated with helicity reversal and occurs through [1,2]- and [1,3]-two ring flips of one...