The immunogenicity of anti-TNF therapy in immune-mediated inflammatory diseases: a systematic review of the literature with a meta-analysis

Volume: 72, Issue: 12, Pages: 1947 - 1955
Published: Dec 6, 2012
Abstract
Immunogenicity of aTNFs is one of the mechanisms behind treatment failure.To assess the effect of anti-drug antibodies (ADA) on drug response to infliximab, adalimumab and etanercept, and the effect of immunosuppression on ADA detection, in patients with Rheumatoid Arthritis, Spondyloarthritis, Psoriasis and Inflammatory Bowel Diseases.PubMed, EMBASE, Cochrane databases, article reference lists (through August 19 2012).Out of 2082 studies, 17...
Paper Details
Title
The immunogenicity of anti-TNF therapy in immune-mediated inflammatory diseases: a systematic review of the literature with a meta-analysis
Published Date
Dec 6, 2012
Volume
72
Issue
12
Pages
1947 - 1955
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