Effect of NR3C2 genetic polymorphisms on the blood pressure response to enalapril treatment
Abstract
The mineralocorticoid receptor (MR; also known as NR3C2) plays important roles in the modulation of blood pressure. The effect of NR3C2 polymorphisms on antihypertensive response to enalapril was investigated.Two hundred and seventy nine essential hypertension patients treated with enalapril were genotyped for two NR3C2 tagSNPs, rs5522 and rs2070950, by Sequenom MassArray™ technology.The reductions in diastolic blood pressure (DBP) were...
Paper Details
Title
Effect of NR3C2 genetic polymorphisms on the blood pressure response to enalapril treatment
Published Date
Feb 1, 2014
Journal
Volume
15
Issue
2
Pages
201 - 208
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