The M1 and M2 paradigm of macrophage activation: time for reassessment
Abstract
Macrophages are endowed with a variety of receptors for lineage-determining growth factors, T helper (Th) cell cytokines, and B cell, host, and microbial products. In tissues, macrophages mature and are activated in a dynamic response to combinations of these stimuli to acquire specialized functional phenotypes. As for the lymphocyte system, a dichotomy has been proposed for macrophage activation: classic vs. alternative, also M1 and M2,...
Paper Details
Title
The M1 and M2 paradigm of macrophage activation: time for reassessment
Published Date
Mar 3, 2014
Journal
Volume
6
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Notes
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