Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation
Abstract
Hypocretin (orexin; Hcrt)-containing neurons of the hypothalamus are essential for the normal regulation of sleep and wake behaviors and have been implicated in feeding, anxiety, depression, and reward. The absence of these neurons causes narcolepsy in humans and model organisms. However, little is known about the molecular phenotype of these cells; previous attempts at comprehensive profiling had only limited sensitivity or were inaccurate. We...
Paper Details
Title
Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation
Published Date
Mar 1, 2013
Journal
Volume
27
Issue
5
Pages
565 - 578
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