Tertiary structure prediction and identification of druggable pocket in the cancer biomarker – Osteopontin-c
Abstract
Osteopontin (Eta, secreted sialoprotein 1, opn) is secreted from different cell types including cancer cells. Three splice variant forms namely osteopontin-a, osteopontin-b and osteopontin-c have been identified. The main astonishing feature is that osteopontin-c is found to be elevated in almost all types of cancer cells. This was the vital point to consider it for sequence analysis and structure predictions which provide ample chances for...
Paper Details
Title
Tertiary structure prediction and identification of druggable pocket in the cancer biomarker – Osteopontin-c
Published Date
Jan 8, 2014
Volume
13
Issue
1
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