Genetic adaptation to high altitude in the Ethiopian highlands
Abstract
Genomic analysis of high-altitude populations residing in the Andes and Tibet has revealed several candidate loci for involvement in high-altitude adaptation, a subset of which have also been shown to be associated with hemoglobin levels, including EPAS1, EGLN1, and PPARA, which play a role in the HIF-1 pathway. Here, we have extended this work to high- and low-altitude populations living in Ethiopia, for which we have measured hemoglobin...
Paper Details
Title
Genetic adaptation to high altitude in the Ethiopian highlands
Published Date
Jan 1, 2012
Volume
13
Issue
1
Pages
R1 - R1
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