Review paper
Melatonin, hydroxyl radical‐mediated oxidative damage, and aging: A hypothesis
Abstract
: Melatonin is a very potent and efficient endogenous radical scavenger. The pineal indolamine reacts with the highly toxic hydroxyl radical and provides on‐site protection against oxidative damage to biomolecules within every cellular compartment. Melatonin acts as a primary non‐enzymatic antioxidative defense against the devastating actions of the extremely reactive hydroxyl radical. Melatonin and structurally related tryptophan metabolites...
Paper Details
Title
Melatonin, hydroxyl radical‐mediated oxidative damage, and aging: A hypothesis
Published Date
May 1, 1993
Journal
Volume
14
Issue
4
Pages
151 - 168
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