Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota

Volume: 172, Issue: 4, Pages: 992 - 1004
Published: Nov 24, 2014
Abstract
Background and Purpose Hydrogen sulphide is an important mediator of gastrointestinal mucosal defence. The use of non-steroidal anti-inflammatory drugs (NSAIDs) is significantly limited by their toxicity in the gastrointestinal tract. Particularly concerning is the lack of effective preventative or curative treatments for NSAID-induced intestinal damage and bleeding. We evaluated the ability of a hydrogen sulphide donor to protect against...
Paper Details
Title
Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota
Published Date
Nov 24, 2014
Volume
172
Issue
4
Pages
992 - 1004
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