Early Changes in Postprandial Insulin Secretion, Not in Insulin Sensitivity, Characterize Juvenile Obesity
Abstract
The development of hyperinsulinemia and insulin resistance, both common in adults with established obesity, was studied in 16 children, weighing 169 ± 8% ideal body weight who were 12.7 ± 0.4 years of age with obesity duration of 0.5–8.5 years and continuous weight gain in excess of normal, and compared with 11 age-matched normal children. Early in the evolution of obesity, insulin and C-peptide responses to a normal meal were increased by 76...
Paper Details
Title
Early Changes in Postprandial Insulin Secretion, Not in Insulin Sensitivity, Characterize Juvenile Obesity
Published Date
May 1, 1994
Journal
Volume
43
Issue
5
Pages
696 - 702
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