Presence of parieto-temporal symptomatology distinguishes early and late onset Alzheimer's disease

Thirty‐one patients with early onset Alzheimer's disease (EAD) and 44 with late onset Alzheimer's disease (LAD) were examined with regard to symptoms reflecting disturbances in various brain regions, ie frontal, parietal and subcortical symptoms. Clinical vascular factors were recorded. The albumin ratio (CSF albumin/serum albumin) was used as a measure of the blood‐brain barrier (BBB) function. Parietal symptoms were more common in EAD than in...