Targeted Quantification of C-Reactive Protein and Cystatin C and Its Variants by Immuno-MALDI-MS
Abstract
The most common technologies for quantitative determination of protein biomarkers are immunoassays, which exist in various formats. Immunoassays offer sensitive and fast protein quantification, but can hardly discriminate between protein variants. Post-translational modifications and genetic variants increase protein microheterogeneity and may play important roles in biological processes. Mass spectrometry combined with immunoaffinity enrichment...
Paper Details
Title
Targeted Quantification of C-Reactive Protein and Cystatin C and Its Variants by Immuno-MALDI-MS
Published Date
May 28, 2014
Journal
Volume
86
Issue
12
Pages
5807 - 5814
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