Mechanisms of Insulin Resistance in Humans and Possible Links With Inflammation
Abstract
Insulin resistance is a major player in the pathogenesis of the metabolic syndrome and type 2 diabetes, and yet, the mechanisms responsible for it remain poorly understood. Magnetic resonance spectroscopy studies in humans suggest that a defect in insulin-stimulated glucose transport in skeletal muscle is the primary metabolic abnormality in insulin-resistant type 2 diabetics. Fatty acids appear to cause this defect in glucose transport by...
Paper Details
Title
Mechanisms of Insulin Resistance in Humans and Possible Links With Inflammation
Published Date
May 1, 2005
Journal
Volume
45
Issue
5
Pages
828 - 833
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History