A SNP in the ABCC11 gene is the determinant of human earwax type
Abstract
Human earwax consists of wet and dry types. Dry earwax is frequent in East Asians, whereas wet earwax is common in other populations. Here we show that a SNP, 538G --> A (rs17822931), in the ABCC11 gene is responsible for determination of earwax type. The AA genotype corresponds to dry earwax, and GA and GG to wet type. A 27-bp deletion in ABCC11 exon 29 was also found in a few individuals of Asian ancestry. A functional assay demonstrated that...
Paper Details
Title
A SNP in the ABCC11 gene is the determinant of human earwax type
Published Date
Jan 29, 2006
Journal
Volume
38
Issue
3
Pages
324 - 330
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