Neurofilaments at a glance

Neurofilaments (NFs) are intermediate filaments with a diameter of 10 nm, similar to that of neurons. Although they are present in perikarya and dendrites, neurofilaments are particularly abundant in axons, where they are essential for the radial growth of axons during development, the maintenance of axon caliber and the transmission of electrical impulses along axons, i.e. velocity of nerve conduction (Eyer and Peterson, 1994; Friede and...