Match!

Change in Hepatitis A Seroprevalence among U.S. Children and Adolescents: Results from the National Health and Nutrition Examination Survey 2003–2006 and 2007–2010

Published on Apr 10, 2013in Vaccine3.269
· DOI :10.3390/vaccines1020105
Deanna Kruszon-Moran25
Estimated H-index: 25
,
R. Klevens1
Estimated H-index: 1
,
Geraldine M. McQuillan35
Estimated H-index: 35
Abstract
To examine changes in seroprevalence of antibodies to hepatitis A virus (HAV) during a period in which universal vaccine recommendations for all U.S. children were implemented, results from serologic testing from the National Health and Nutrition Examination Survey (NHANES) from 2003–2010 were analyzed among 7,989 participants age 6–19 years, born in the U.S. in two birth cohorts (1986–1996 and 1997–2004). Overall prevalence increased over time from 24.4% in 2003–2006 to the highest ever reported (37.6%) in 2007–2010. Specifically, increases reached statistical significance in the birth cohort born in the years after implementation of vaccine recommendations (1997–2004), among those of race/ethnicity other than white, non-Hispanic, and among states where recommendations were implemented later. The greatest increase over time was among the subgroup of persons in states with early implementation who were of race/ethnicity other than white, non-Hispanic. Geographic region and birth cohort based on vaccine recommendations as well as race/ethnicity were the main predictors of seropositivity in 2007–2010. The increase in Hepatitis A seroprevalence occurred during a time of decreasing incidence and increasing vaccination, however race/ethnic disparities persist.
  • References (14)
  • Citations (3)
📖 Papers frequently viewed together
20 Citations
18 Citations
20083.27Vaccine
160 Citations
78% of Scinapse members use related papers. After signing in, all features are FREE.
References14
Newest
#1Maria Chironna (University of Bari)H-Index: 22
#2Rosa Prato (University of Foggia)H-Index: 20
Last. Cinzia Germinario (University of Bari)H-Index: 22
view all 7 authors...
Background Raw seafood consumption was identified as the major risk factor for hepatitis A during the large epidemic of 1996 and 1997 in Puglia (South Italy). In Puglia, vaccination for toddlers and preadolescents has been recommended since 1998. The aim of the study was to evaluate the incidence, seroprevalence, molecular epidemiology, and environmental circulation of hepatitis A virus (HAV) in Puglia more than ten years after the introduction of anti-HAV vaccination in the regional immunizatio...
22 CitationsSource
#1Christina DorellH-Index: 16
#2David YankeyH-Index: 22
Last. Trudy V. MurphyH-Index: 29
view all 4 authors...
OBJECTIVE: Hepatitis A infection causes severe disease among adolescents and adults. The Advisory Committee on Immunization Practices instituted incremental recommendations for hepatitis A vaccination (HepA) at 2 years of age based on risk (1996), in selected states (1999), and universally at 1 year of age, with vaccination through 18 years of age based on risk or desire for protection (2006). We assessed adolescent HepA coverage in the United States and factors independently associated with vac...
25 CitationsSource
#1Marta N. Vacchino (National University of Mar del Plata)H-Index: 2
Summary. In Argentina, the annual incidence rate of reported hepatitis A disease ranged from 70.5 to 173.8 per 100 000 during 1995–2004. A single dose universal hepatitis A immunization program aimed at children aged 12 months was started in June 2005. The aim was to observe the impact of universal vaccination against hepatitis A in Argentina. A longitudinal analysis of hepatitis A rates reported in Argentina since 1995 to the National Notifiable Diseases Surveillance System (SINAVE). Incidence ...
76 CitationsSource
#1Annemarie Wasley (CDC: Centers for Disease Control and Prevention)H-Index: 14
#2Taraz SamandariH-Index: 16
Last. Beth P. BellH-Index: 54
view all 3 authors...
ContextIn the United States, hepatitis A is a frequently reported vaccine-preventable disease. Vaccination has been recommended for persons at increased risk since 1996. In 1999, it was recommended that children living in 11 states with the highest incidence of hepatitis A be routinely vaccinated, and that children living in 6 additional states, with incidence above the national average, be considered for routine vaccination.ObjectiveTo assess impact of the current vaccination strategy by evalua...
219 CitationsSource
Abstract The application of epidemiological techniques is important at all stages in the development of a vaccination programme. Before licensing, the safety and efficacy of a new vaccine must be determined in carefully designed clinical trials. An epidemiological assessment of the disease is then needed in order to formulate an appropriate strategy for delivery of the vaccine. Once the vaccine has been introduced into routine use, continued evaluation, both of the vaccine and the programme, is ...
49 CitationsSource
Cited By3
Newest
#1Doracelly Hincapié (UdeA: University of Antioquia)H-Index: 3
#2Marcela Acevedo (UdeA: University of Antioquia)
Last. Elkin OsorioH-Index: 2
view all 24 authors...
Introduction: Serological surveillance (serosurveillance) provides the most direct measure of herd immunity of vaccine preventable diseases. Little is known about the opportunities and challenges of serosurveillance experiences, particularly pertussis. Objective: To describe the process of serosurveillance for vaccine preventable diseases with an emphasis on the experience of pertussis in the metropolitan area of Antioquia (Valle de Aburra) in 2015-2016 and analyze the contributions and challeng...
Source
#1Guan-Jhou Chen (NTU: National Taiwan University)H-Index: 4
#2Kuan-Yin Lin (NTU: National Taiwan University)H-Index: 7
Last. Shan-Chwen Chang (NTU: National Taiwan University)H-Index: 56
view all 4 authors...
17 CitationsSource