Effects of Cardiac Resynchronization Therapy on Muscle Sympathetic Nerve Activity

Introduction Muscle sympathetic nerve activity (MSNA) is an independent prognostic marker in patients with heart failure (HF). Therefore, its relevance to the treatment of HF patients is unquestionable. Objectives In this study, we investigated the effects of cardiac resynchronization therapy (CRT) on MSNA response at rest and during exercise in patients with advanced HF . Methods We assessed 11 HF patients (51 ± 3.4 years; New York Heart...