The role of anticytokine therapy in heart failure: recent lessons from preclinical and clinical trials?

Volume: 87, Issue: 2, Pages: 419 - 440
Published: Mar 1, 2003
Abstract
In summary, over a decade of investigation has demonstrated the pathophysiologic importance of TNF in the development and progression of cardiac dilatation and heart failure. Although the signaling pathways that regulate the cardiac production of TNF have not yet been identified and the potential benefits of TNF expression to the heart are not understood, the benefits of anticytokine therapy in animal models is marked. Unfortunately, these...
Paper Details
Title
The role of anticytokine therapy in heart failure: recent lessons from preclinical and clinical trials?
Published Date
Mar 1, 2003
Volume
87
Issue
2
Pages
419 - 440
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