Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation.
Abstract
Adiponectin is secreted from adipocytes, and low circulating levels have been epidemiologically associated with obesity, insulin resistance, type 2 diabetes, and cardiovascular disease. To investigate whether adiponectin could exert autocrine effects in adipocytes, we expressed the adiponectin gene in 3T3-L1 fibroblasts. We observed that 3T3-L1 fibroblasts expressing adiponectin have a fast growth phase and reach confluence more rapidly compared...
Paper Details
Title
Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation.
Published Date
Jul 1, 2005
Journal
Volume
46
Issue
7
Pages
1369 - 1379
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