Restless legs syndrome outside the blood–brain barrier – Exacerbation by domperidone in Parkinson's disease

Volume: 19, Issue: 1, Pages: 92 - 94
Published: Jan 1, 2013
Abstract
IntroductionModels of dopaminergic function in restless legs focus on central dopaminergic neurons. Domperidone, a peripheral dopamine blocker that cannot cross the blood–brain barrier, is commonly used in Parkinson's disease. After encountering a case of restless legs syndrome that dramatically worsened with domperidone, we assessed whether Parkinson's patients may have exacerbation of restless legs with domperidone.MethodsFrom two Parkinson's...
Paper Details
Title
Restless legs syndrome outside the blood–brain barrier – Exacerbation by domperidone in Parkinson's disease
Published Date
Jan 1, 2013
Journal
Volume
19
Issue
1
Pages
92 - 94
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