Genome-wide CpG island methylation analyses in non-small cell lung cancer patients
Abstract
DNA methylation is part of the epigenetic gene regulation complex, which is relevant for the pathogenesis of cancer. We performed a genome-wide search for methylated CpG islands in tumors and corresponding non-malignant lung tissue samples of 101 stages I-III non-small cell lung cancer (NSCLC) patients by combining methylated DNA immunoprecipitation and microarray analysis. Overall, we identified 2414 genomic positions differentially methylated...
Paper Details
Title
Genome-wide CpG island methylation analyses in non-small cell lung cancer patients
Published Date
Nov 19, 2012
Journal
Volume
34
Issue
3
Pages
513 - 521
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