Diet‐induced obesity accelerates the onset of terminal phenotypes in α‐synuclein transgenic mice
Abstract
Parkinson's disease (PD) and diabetes belong to the most common neurodegenerative and metabolic syndromes, respectively. Epidemiological links between these two frequent disorders are controversial. The neuropathological hallmarks of PD are protein aggregates composed of amyloid-like fibrillar and serine-129 phosphorylated (pS129) α-synuclein (AS). To study if diet-induced obesity could be an environmental risk factor for PD-related...
Paper Details
Title
Diet‐induced obesity accelerates the onset of terminal phenotypes in α‐synuclein transgenic mice
Published Date
Aug 11, 2014
Journal
Volume
131
Issue
6
Pages
848 - 858
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