CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation

Volume: 45, Issue: 1, Pages: 273 - 297
Published: Nov 7, 2011
Abstract
Bacteria and archaea have evolved defense and regulatory mechanisms to cope with various environmental stressors, including virus attack. This arsenal has been expanded by the recent discovery of the versatile CRISPR-Cas system, which has two novel features. First, the host can specifically incorporate short sequences from invading genetic elements (virus or plasmid) into a region of its genome that is distinguished by clustered regularly...
Paper Details
Title
CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation
Published Date
Nov 7, 2011
Volume
45
Issue
1
Pages
273 - 297
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