Metagenomic microbial community profiling using unique clade-specific marker genes
Abstract
Metagenomic shotgun sequencing data can identify microbes populating a microbial community and their proportions, but existing taxonomic profiling methods are inefficient for increasingly large data sets. We present an approach that uses clade-specific marker genes to unambiguously assign reads to microbial clades more accurately and >50× faster than current approaches. We validated our metagenomic phylogenetic analysis tool, MetaPhlAn, on...
Paper Details
Title
Metagenomic microbial community profiling using unique clade-specific marker genes
Published Date
Jun 10, 2012
Journal
Volume
9
Issue
8
Pages
811 - 814
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