Why do cancers have high aerobic glycolysis

Volume: 4, Issue: 11, Pages: 891 - 899
Published: Nov 1, 2004
Abstract
If carcinogenesis occurs by somatic evolution, then common components of the cancer phenotype result from active selection and must, therefore, confer a significant growth advantage. A near-universal property of primary and metastatic cancers is upregulation of glycolysis, resulting in increased glucose consumption, which can be observed with clinical tumour imaging. We propose that persistent metabolism of glucose to lactate even in aerobic...
Paper Details
Title
Why do cancers have high aerobic glycolysis
Published Date
Nov 1, 2004
Volume
4
Issue
11
Pages
891 - 899
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.