Prefronto-subcortical imbalance characterizes poor decision-making: neurochemical and neural functional evidences in rats
Abstract
A major challenge of decision-making research in recent years has been to develop models of poor decision-making to identify its neural bases. Toward this goal, we developed a Rat Gambling Task that discerns good and poor decision-makers in a complex and conflicting situation such as the human Iowa Gambling Task. Nothing is known about the role of the monoaminergic modulatory systems in shaping these phenotypes. Moreover, functional and temporal...
Paper Details
Title
Prefronto-subcortical imbalance characterizes poor decision-making: neurochemical and neural functional evidences in rats
Published Date
Aug 19, 2014
Journal
Volume
220
Issue
6
Pages
3485 - 3496
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