Targeted genome editing in primate embryos
Abstract
Mosaic mutations and off-target effects caused by CRISPR/Cas9 have led to concerns about the efficiency and specificity of this new technique in non-human primates and other large animals. Here we discuss recent findings from primate embryos, with a focus on the technical issues CRISPR/Cas9 faces before producing non-human primate models of human...
Paper Details
Title
Targeted genome editing in primate embryos
Published Date
Jun 2, 2015
Journal
Volume
25
Issue
7
Pages
767 - 768
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History