SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler
Abstract
There is a rapidly increasing amount of de novo genome assembly using next-generation sequencing (NGS) short reads; however, several big challenges remain to be overcome in order for this to be efficient and accurate. SOAPdenovo has been successfully applied to assemble many published genomes, but it still needs improvement in continuity, accuracy and coverage, especially in repeat regions.To overcome these challenges, we have developed its...
Paper Details
Title
SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler
Published Date
Dec 1, 2012
Journal
Volume
1
Issue
1
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