Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells
Abstract
Differentiation of human embryonic stem cells (hESCs) provides a unique opportunity to study the regulatory mechanisms that facilitate cellular transitions in a human context. To that end, we performed comprehensive transcriptional and epigenetic profiling of populations derived through directed differentiation of hESCs representing each of the three embryonic germ layers. Integration of whole-genome bisulfite sequencing, chromatin...
Paper Details
Title
Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells
Published Date
May 1, 2013
Journal
Volume
153
Issue
5
Pages
1149 - 1163
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