Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer
Abstract
Reprogramming somatic cells into pluripotent embryonic stem cells (ESCs) by somatic cell nuclear transfer (SCNT) has been envisioned as an approach for generating patient-matched nuclear transfer (NT)-ESCs for studies of disease mechanisms and for developing specific therapies. Past attempts to produce human NT-ESCs have failed secondary to early embryonic arrest of SCNT embryos. Here, we identified premature exit from meiosis in human oocytes...
Paper Details
Title
Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer
Published Date
Jun 1, 2013
Journal
Volume
153
Issue
6
Pages
1228 - 1238
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