Age‐dependent changes in matrix composition and organization at the ligament‐to‐bone insertion

Injuries to the anterior cruciate ligament (ACL) often occur at the ligament‐to‐bone insertion site; thus, an in‐depth understanding of the native insertion is critical in identifying the etiology of failure and devising optimal treatment protocols for ACL injuries. The objective of this study is to conduct a systematic characterization of the ACL‐to‐bone interface, focusing on structural and compositional changes as a function of age. Using a...