Plasmablasts as a biomarker for IgG4-related disease, independent of serum IgG4 concentrations
Abstract
We examined the utility of circulating total and IgG4+ plasmablasts as biomarkers of diagnosis and disease activity in IgG4-related disease (IgG4-RD).We evaluated patients with active, untreated, biopsy-proven IgG4-RD affecting various organs. Flow cytometry was used to measure total plasmablast and IgG4+ plasmablast counts by gating peripheral blood for CD19lowCD38+CD20-CD27+ cells and CD19lowCD38+CD20-CD27+IgG4+ cells. Serum IgG4...
Paper Details
Title
Plasmablasts as a biomarker for IgG4-related disease, independent of serum IgG4 concentrations
Published Date
May 9, 2014
Volume
74
Issue
1
Pages
190 - 195
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