(NZ)CH...O Contacts assist crystallization of a ParB-like nuclease

Volume: 7, Issue: 1
Published: Jul 7, 2007
Abstract
Background The major bottleneck for determination of 3 D structures of proteins using X-rays is the production of diffraction quality crystals. Often proteins are subjected to chemical modification to improve the chances of crystallization Results Here, we report the successful crystallization of a nuclease employing a reductive methylation protocol. The key to crystallization was the successful introduction of 44 new cohesive (NZ) CH...O...
Paper Details
Title
(NZ)CH...O Contacts assist crystallization of a ParB-like nuclease
Published Date
Jul 7, 2007
Volume
7
Issue
1
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