Internal medicine

Receptor

Prazosin

Biology

Envenomation

Intensive care medicine

Ecology

Antagonist

Scorpion

Venom

Anesthesia

Medicine

Human & Experimental Toxicology

Scorpion stings represent an important and serious public health problem worldwide due to their high incidence and potentially severe and often fatal clinical manifestations. Children are at greater risk of developing severe cardiac, respiratory, and neurological complications due to lesser body surface area. Alpha receptor stimulation plays important role in the pathogenesis of pulmonary edema. Prazosin, a post synaptic alpha blocker, can be recommended as an effective drug in the treatment of serious scorpion envenomations with significant sympathetic symptoms. Oral prazosin is fast acting, easily available, relatively cheap, free from any anaphylaxis and highly effective.

Prazosin treatment in the management of scorpion envenomation