Neutrophil elastase regulates both type 1 and type 2 immune responses to enteric infection (MPF1P.800)
Volume: 192, Issue: 1_Supplement, Pages: 66.19 - 66.19
Published: May 1, 2014
Abstract
Local neutrophil influx occurs in response to enteric bacterial as well as nematode infection. Neutrophilic release of the serine protease, elastase (NE), is implicated in host defense as well as tissue injury. The aim of this study was to determine the contribution of elastase in host defense against enteric pathogens that induce a Th1/Th17 or a Th2 immune response. Elastase deficient (ELA1-/-) or C57BL/6 (WT) mice (n=5-7) were inoculated with...
Paper Details
Title
Neutrophil elastase regulates both type 1 and type 2 immune responses to enteric infection (MPF1P.800)
Published Date
May 1, 2014
Journal
Volume
192
Issue
1_Supplement
Pages
66.19 - 66.19
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