Review paper
Chemical biology of anticancer gold(iii ) and gold(i ) complexes
Abstract
Gold complexes have recently gained increasing attention in the design of new metal-based anticancer therapeutics. Gold(III) complexes are generally reactive/unstable under physiological conditions via intracellular redox reactions, and the intracellular Au(III) to Au(I) reduction reaction has recently been "traced" by the introduction of appropriate fluorescent ligands. Similar to most Au(I) complexes, Au(III) complexes can inhibit the...
Paper Details
Title
Chemical biology of anticancer gold(iii ) and gold(i ) complexes
Published Date
Jan 1, 2015
Journal
Volume
44
Issue
24
Pages
8786 - 8801
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